|
Neoplasms
|
0.050 |
Biomarker
|
group |
BEFREE |
Furthermore, PLCε shRNA reduced the tumor xenograft growth implanted with BIU-87 cells.
|
21705050 |
2011 |
|
Neoplasms
|
0.050 |
Biomarker
|
group |
BEFREE |
By knocking out the PRIP gene in the tumor cell line, we demonstrated that PRIP deficiency led to inhibited tumor formation without affecting tumor cell proliferation.
|
19329434 |
2009 |
|
Neoplasms
|
0.050 |
Biomarker
|
group |
BEFREE |
Here, it is demonstrated that phospholipase C-like 1/uncoupling protein 1 (PLCL1)/(UCP1)-mediated lipid browning promotes tumor cell "slimming" and represses tumor progression.
|
31131187 |
2019 |
|
Neoplasms
|
0.050 |
Biomarker
|
group |
BEFREE |
A xenograft tumor mouse model also demonstrated similar results as the in vitro experiments, further confirming the role of PLCε in regulating bladder cell growth in vivo.
|
30864733 |
2019 |
|
Neoplasms
|
0.050 |
Biomarker
|
group |
BEFREE |
Tumor suppressor role of phospholipase C epsilon in Ras-triggered cancers.
|
24591640 |
2014 |
|
Malignant Neoplasms
|
0.040 |
Biomarker
|
group |
BEFREE |
The controversial role of phospholipase C epsilon (PLCε) in cancer development and progression.
|
28382133 |
2017 |
|
Malignant Neoplasms
|
0.040 |
GeneticVariation
|
group |
BEFREE |
Polymorphisms in the phospholipase C epsilon (PLCE) 1 gene play a crucial role in the development and progression of several types of cancer.
|
28418898 |
2017 |
|
Malignant Neoplasms
|
0.040 |
Biomarker
|
group |
BEFREE |
Phospholipase Cε (PLCε), a key regulator of diverse cellular functions, has been implicated in various malignancies.
|
25796442 |
2015 |
|
Malignant Neoplasms
|
0.040 |
Biomarker
|
group |
BEFREE |
Phospholipase Cε (PLCε), an oncogene, has been found to be involved in the carcinogenesis, tumor proliferation and migration of several types of cancer.
|
30864728 |
2019 |
|
Esophageal Neoplasms
|
0.030 |
GeneticVariation
|
group |
BEFREE |
Multiple studies with large clinic-based cohorts revealed that variations of the phospholipase C epsilon (PLCE1) gene were associated with esophageal cancer susceptibility.
|
28147304 |
2017 |
|
Esophageal Neoplasms
|
0.030 |
AlteredExpression
|
group |
BEFREE |
To investigate the effect and mechanism of phospholipase C epsilon gene 1 (<i>PLCE1</i>) expression on esophageal cancer cell lines.
|
30450849 |
2018 |
|
Esophageal Neoplasms
|
0.030 |
GeneticVariation
|
group |
BEFREE |
A single-nucleotide polymorphism (rs2274223: A5780G:His1927Arg) in the phospholipase C epsilon gene (PLCϵ) was recently identified as a susceptibility locus for esophageal cancer in Chinese subjects.
|
23390063 |
2013 |
|
Primary malignant neoplasm
|
0.030 |
GeneticVariation
|
group |
BEFREE |
Polymorphisms in the phospholipase C epsilon (PLCE) 1 gene play a crucial role in the development and progression of several types of cancer.
|
28418898 |
2017 |
|
Primary malignant neoplasm
|
0.030 |
Biomarker
|
group |
BEFREE |
The controversial role of phospholipase C epsilon (PLCε) in cancer development and progression.
|
28382133 |
2017 |
|
Primary malignant neoplasm
|
0.030 |
Biomarker
|
group |
BEFREE |
Phospholipase Cε (PLCε), an oncogene, has been found to be involved in the carcinogenesis, tumor proliferation and migration of several types of cancer.
|
30864728 |
2019 |
|
Nephrotic Syndrome
|
0.010 |
GeneticVariation
|
group |
BEFREE |
Using positional cloning, we identified mutations in the phospholipase C epsilon gene (PLCE1) as causing early-onset nephrotic syndrome with end-stage kidney disease.
|
17086182 |
2006 |
|
Body Height
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
|
30595370 |
2019 |
|
Bone Density
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Life-Course Genome-wide Association Study Meta-analysis of Total Body BMD and Assessment of Age-Specific Effects.
|
29304378 |
2018 |
|
Circadian Rhythms
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
GWAS of 89,283 individuals identifies genetic variants associated with self-reporting of being a morning person.
|
26835600 |
2016 |
|
Intelligence
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence.
|
29942086 |
2018 |
|
Intelligence
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.
|
29844566 |
2018 |
|
Sodium measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
GWAS for urinary sodium and potassium excretion highlights pathways shared with cardiovascular traits.
|
31409800 |
2019 |
|
High density lipoprotein measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
A common variant association study reveals novel susceptibility loci for low HDL-cholesterol levels in ethnic Arabs.
|
26879886 |
2016 |
|
mathematical ability
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.
|
30038396 |
2018 |
|
Finding of Mean Corpuscular Hemoglobin
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
|
30595370 |
2019 |